Lu Chen, Shanghai Jiao Tong Univerisity


		Lu Chen Associate Professor X-LANCE Lab, School of Computer Science, Shanghai Jiao Tong University Shanghai Innovation Institution (SII) Email: chenlusz [AT] sjtu [DOT] edu [DOT] cn Address: 800 Dongchuan Road, Shanghai 200240, China

Lu Chen

Associate Professor
X-LANCE Lab, School of Computer Science, Shanghai Jiao Tong University
Shanghai Innovation Institution (SII)

Email: chenlusz [AT] sjtu [DOT] edu [DOT] cn
Address: 800 Dongchuan Road, Shanghai 200240, China

Large Language Models (LLM) Group @SJTU X-LANCE Lab

     We are looking for Ph.D./master/undergraduate students and postdocs interested in Large Language Models (LLMs) and AI for Science. Please send your CV to me if you want to join us.
     2025-03-20：正在招收2025年09月入学的普博生，方向为大模型与 AI for Science 的交叉方向，涉及大模型后训练、强化学习推理、大模型智能体、多模态大模型等细分方向，欢迎感兴趣的同学联系. 【招生启事】
     2025-09-22：预计招收1-2名2026年入学的上海创智学院联培博士（普博生/硕转博），感兴趣的同学欢迎联系并关注上海创智学院金秋营招生信息.

Research Interests

Natural Language Processing: Dialogue Systems, Large Language Models
AI for Science: AI for Materials Science, AI for Life Science

Teaching

Natural Language Processing for CS&AI undergraduates at SJTU, 2021/2022/2023/2024 Fall
Knowledge Representation and Reasoning for AI undergraduates at SJTU, 2022/2023/2024 Spring

Selected Publication [Google Scholar]

Pre-Training, Alignment, Inference for Large Language Models

Task-Specific Data Selection for Instruction Tuning via Monosemantic Neuronal Activations
Da Ma, Gonghu Shang, Zhi Chen, Libo Qin, Yijie Luo, Hongshen Xu, Lei Pan, Shuai Fan, Lu Chen, Kai Yu
NeurIPS 2025 [Paper]
Heads up! Large Language Models Can Perform Tasks Without Your Instruction via Selective Attention Head Masking
Senyu Han, Hongchuan Zeng, Kai Yu, Lu Chen
ICML 2025 [Paper]
Reducing Tool Hallucination via Reliability Alignment
Hongshen Xu, Zichen Zhu, Lei Pan, Zihan Wang, Su Zhu, Da Ma, Ruisheng Cao, Lu Chen, Kai Yu
ICML 2025 [Paper]
Evolving Subnetwork Training for Large Language Models
Hanqi Li, Lu Chen, Da Ma, Zijian Wu, Su Zhu, Kai Yu
ICML 2024 [Paper]

Autonomous Agents with Large Language Models

NeuSym-RAG: Hybrid Neural Symbolic Retrieval with Multiview Structuring for PDF Question Answering
Ruisheng Cao, Hanchong Zhang, Tiancheng Huang, Zhangyi Kang, Yuxin Zhang, Liangtai Sun, Hanqi Li, Yuxun Miao, Shuai Fan, Lu Chen, Kai Yu
ACL 2025 [Paper][Code]
MobA: Multifaceted Memory-Enhanced Adaptive Planning for Efficient Mobile Task Automation
Zichen Zhu, Hao Tang, Yansi Li, Dingye Liu, Hongshen Xu, Kunyao Lan, Danyang Zhang, Yixuan Jiang, Hao Zhou, Chenrun Wang, Situo Zhang, Liangtai Sun, Yixiao Wang, Yuheng Sun, Lu Chen, Kai Yu
NAACL 2025 (Demo Track) [Paper][Code]
IBSEN: Director-Actor Agent Collaboration for Controllable and Interactive Drama Script Generation
Senyu Han, Lu Chen, Li-Min Lin, Zhengshan Xu, Kai Yu
ACL 2024 [Paper][Website]
Large Language Models Are Semi-Parametric Reinforcement Learning Agent
Danyang Zhang, Lu Chen, Situo Zhang, Hongshen Xu, Zihan Zhao, Kai Yu
NeurIPS 2023 [Paper] [Code]

Large Language Models for Science

MS-BART: Unified Modeling of Mass Spectra and Molecules for Structure Elucidation
Yang Han, Pengyu Wang, Kai Yu, Xin Chen, Lu Chen
NeurIPS 2025 [Paper]
Developing ChemDFM as A Large Language Foundation Model for Chemistry
Zihan Zhao^*, Da Ma^*, Lu Chen, Liangtai Sun, Zihao Li, Yi Xia, Bo Chen, Hongshen Xu, Zichen Zhu, Su Zhu, Shuai Fan, Guodong Shen, Kai Yu, Xin Chen
Cell Reports Physical Science, 2025. [Paper][Code][HuggingFace][央视新闻联播]
ChemDFM-X: Towards Large Multimodal Model for Chemistry
Zihan Zhao^*, Bo Chen^*, Jingpiao Li, Lu Chen, Liyang Wen, Pengyu Wang, Zichen Zhu, Danyang Zhang, Ziping Wan, Yansi Li, Zhongyang Dai, Xin Chen, Kai Yu
Science China Information Sciences, 2024. [Paper][Code][HuggingFace]
SciEval: A Multi-Level Large Language Model Evaluation Benchmark for Scientific Research
Liangtai Sun, Yang Han, Zihan Zhao, Da Ma, Zhennan Shen, Baocai Chen, Lu Chen, Kai Yu
AAAI 2024 [Paper][Website]

Professional Services

Action Editor/Area Chair

ACL Rolling Review (ARR)

Programme Committee Member

ACL(Main/Demo Track), NAACL(Main/Demo Track), EMNLP, AAAI, NeurIPS, ICML

Journal Reviewer

Nature
Transactions of the Association for Computational Linguistics (TACL)
IEEE/ACM Transactions on Audio, Speech and Language Processing (TASLP)

Honors and Awards

2022 NCMMSC Best Paper Award
2021 CCF Outstanding Doctoral Dissertation Award Nomination (17 for CS major in China)
2021 ACM (Shanghai Chapter) Outstanding Doctoral Dissertation Award (3 in Shanghai)
2020 Shanghai Jiao Tong University (SJTU) Outstanding Doctoral Dissertation Award (15 in SJTU)
2018 COLING Area Chair Favorites

Last updated on 2025-05. Visitor number: